RELEVANCE OF BLOOD CULTURE TO THE DIAGNOSIS AND TREATMENT OF SEPTICEMIA
- Project Research
- 1-5 Chapters
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 3000
ABSTRACT
A study of septicaemia was conducted in Enugu metropolis with a view to determine the relevance of blood culture to the diagnosis and treatment of this disease. The subjects comprised of Six hundred and fifty (650) children and adults of both sexes aged between one day to 70 years having clinical features suggestive of septicaemia, who were on admission at University Of Nigeria Teaching Hospitals (UNTH), Enugu. Their blood specimens were seeded into thioglycolateand glucose broths and incubated at 37 °C for 7 days. Subcultures were performed after 1, 2, 3, 4 and 7 days respectively. Growth (positivity) in the broths was assessed using conventional diagnostic methods namely macroscopy(visualization), Gram filming (microscopy) and culture. The bacterial isolates harvested were subjected to in-vitroantibiotic susceptibility tests using the disc diffusion method. Etiology was established in 104 out of 350 subjects indicating an incidence of 29.7%.
This difference in prevalence among different age groups was statistically significant(P < 0.01). The males (59/350, 16.86%) appeared to be more susceptible to septicaemia than the females (45/350, 12.9%) in all the age groups.
This variation had no statistical significance (P > 0.01). Monomicrobialsepticaemia had ahigher prevalence (91.3%) than polymicrobialsepticaemia (8.65%). Staphylococcus aureusand Escherichia coliconstituted 33.3%. Most of the offensive microbes were facultative anaerobes (93.3%) while very few were strict aerobes (7.69%) and strict anaerobes (1.92%). The isolated anaerobes were Peptostreptococcussp. (1%) and Bacteroidesfragilis(1%). The in vitro susceptibility of the bacterial isolates to antibiotics indicated 78.9-92.9% sensitivity to vancomycin, zinnat, peflacin and fortum. However, they were 60 – 90% resistant to penicillin, ampicillin, tetracycline and septrin. This study confirmed the diverse nature of bacterial etiologies of septicaemia in Enugu metropolis; the need for the use ofthioglycolate broths, first subcultures on or before 24 h instead of starting off for after 48 h of incubation, complementary application of macroscopy, Gram filming and culture including antibiotic susceptibility test as an integral part of diagnosis and treatment of septicaemia is hereby advocated, most especially in the developing countries of the world.
Related Project Materials
EVALUATION OF THE PROVISION AND MANAGEMENT OF FACILITIES IN SECONDARY SCHOOLS IN ZARIA EDUCATION ZONE, KADUNA STATE, NIGERIA
ABSTRACT
The study was on the evaluation of the provision and management of facilities in secondary schools in Zaria Education Zone, Kadu...
DESIGN AND IMPLEMENTATION OF A COMPUTER-BASED SECURITY INFORMATION SYSTEM
PROJECT SCOPE
The scope of this project depends on the available facilities and resources both human and ma...
AN ASSESSMENT OF THE EFFECT OF E-NAIRA PLATFORM ON NIGERIA COMMERCIAL BANKS
Background Of The Study
Nigeria's financial landscape has never been static. New services and produ...
Course Catalogue Handling System (CCHS)
ABSTRACT
In an academic setting, it is important for students to be well informed about their academic status and progress regularly. All...
ANALYSIS OF MARKETING DISTRIBUTION STRATEGY OF SOME NIGERIAN COMPANIES
ABSTRACT
The analysis of marketing distribution strategies of some Nigerian companies with case study o...
THE IMPACT OF QUALITY LENDING ON BANKS PROFITABILITY
ABSTRACT
This research presents the investigation into the impact of quality lending on banks profitabi...
PROFICIENCY IN ENGLISH LANGUAGE AS A DETERMINANT OF STUDENTS ACADEMIC PERFORMANCE
ABSTRACT
The study examined proficiency in English language as a determinant of students academic performance in seconda...
PHARMACOGNOSTIC, NUTRITIONAL AND TOXICITY STUDIES ON THE AERIAL PART OF DAUCUS CAROTA L. (APIACEAE)
Abstract
Daucus carota (L.) commonly known as carrot belongs to the family of Apiaceae. The aerial part is used as component of livestock...
AN APPRAISAL OF THE LEGAL FRAMEWORK FOR THE PRIVATIZATION AND REFORM PROGRAMME FOR THE ENERGY SECTOR IN NIGERIA
ABSTRACT
This Research Study titled: “AN APPRAISAL OF THE LEGAL FRAMEWORK FOR THE PRIVATIZATION AND REFORM PROGRAMME FOR THE ENERGY...
SUSCEPTIBILITY PROFILES OF SOME BACTERIA ISOLATED FROM STOOL OF DIARRHOEAL PATIENTS TO THE STEM AND ROOT BARKS EXTRACTS OF FICUS SYCOMORUS Linn (Moracae)
ABSTRACT
Effective antibiotic management of diarrhoea caused by bacterial organisms faces challenge of antibiotic resistance which combin...
